Transgenic Mouse Pilot Experiment

This immunogenicity study used transgenic mice that express hu CD4 and hu CCR5 coreceptor. These mice were immunized with:

a) the fusion-competent (FC) vaccine immunogen = COS-env cells with U87-CD4-CCR5 cells

b) U87-CD4-CCR5 cells

c) U87-CD4-CCR5 cells cocultured with mock-transfected COS cells

Which of these are cell controls? answer b and c

Click here for results to this transgenic mouse pilot experiment

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