Replication of M2 Mutant Viruses in Mice

This test was done to support the in vitro results found

Procedure:

1. 5 week old mice were intranasally infected with 50 microliters of each mutant virus type.

2. Lung and nasal tissue were extracted from the mice 3 days post infection.

3. Virus titer was determined by infecting MDCK cells with the extracted tissue.

 

 

Q: Which virus types would you expect to replicate in mice?

Result

Experiment menu