PUBLICATIONS
179. G. Traglia, F. Pasteran, S. Moheb, U. Akhtar, S. Gonzalez, C. Maldonado, N. Furtado, A. Mohamed, J. Escalante, M. Tuttobene, A. Quillen, C. Fontan, E. Albornoz, A. Corso, R. A. Bonomo, G. Rao, M. E. Tolmasky, M. S. Ramirez. Insights into Acinetobacter baumannii AMA205's unprecedented antibiotic resistance International Journal of Molecular Sciences 2024 25 11424 doi:10.3390/ijms252111424 .
178. O. Wong, V. Mezcord, C. Lopez, G. Traglia, F. Pasteran, M. Tuttobene, A. Corso, M. E. Tolmasky, R. A. Bonomo, M. S. Ramirez. Hetero-antagonism of avibactam and sulbactam with cefiderocol in carbapenem-resistant Acinetobacter spp. Microbiology Spectrum 2024 14 19145. doi: 10.1128/spectrum.00930-24.
177. J. Escalante, M. Hamza, B. Nishimura, M. Melecio, C. Davies-Sala, M. Tuttobene, T. Subils, G. Traglia, C. Pham, R. Sieira, L. A. Actis, R. A. Bonomo, M. E. Tolmasky, M. S. Ramirez. Carbapenem-resistant Acinetobacter baumannii (CRAB): metabolic adaptation and transcriptional response to human urine (HU) Scientific Reports 2024 14 19145. doi: 10.1038/s41598-024-70216-w.
176. J. Sklenicka, T. Tran, M. S. Ramirez, H. M. Donow, A. J. Magaña, T. LaVoi, Y. Mamun, V. Jimenez, P. Chapagain, R. Santos, C. Pinilla, M. A. Giulianotti, M. E. Tolmasky. Structure–activity relationship of pyrrolidine pentamine derivatives as inhibitors of the aminoglycoside 6′-N-acetyltransferase Type Ib. Antibiotics 2024 13 672. doi: 10.3390/antibiotics13070672.
175. F. Pasteran, O. Wong, V. Mezcord, C. Lopez, N. Georgeos, V. Fua, A. Ozuna, D. Ramlaoui, C. Sanchez, P. Marchetti, P. Corso, M. E. Tolmasky, R. A. Bonomo, M. S. Ramirez. Comparison of available methods to evaluate cefiderocol susceptibility in Acinetobacter spp. Journal of Microbiology Methods 2024 223 106972. doi: 10.1016/j.mimet.2024.106972.
174. G. M. Traglia, N. Furtado, J. Escalante, M. Almuzara, R. Cittadini, M. Tuttobene, T. Subilis, C. Maldonado, V. Viard, S. Gonzalez, M. Sormani, M. E. Tolmasky, C. Vay, G. Rao, M. S. Ramirez. Dynamic evolution of Achromobacter xylosoxydans in a patient with leukemia receiving antibiotic treatment. International Journal of Antimicrobial Agents 2024. doi: 10.1016/j.ijantimicag.2024.107218
173. V. Mezcord, G. M. Traglia, F. Pasteran, J. Escalante, C. Lopez, O. Wong, L. Rojas, S. Marshall, M. E. Tolmasky, R. A. Bonomo, M. S. Ramirez. Characterization of cefiderocol-resistant spontaneous mutant variants of Klebsiella pneumoniae producing NDM-5 with a single mutation in cirA. International Journal of Antimicrobial Agents 2024 63 107131. doi: 10.1016/j.ijantimicag.2024.107131
172. O. d'Udekem d'Acoz, F. Hue, T. Ye, L. Wang, M. Leroux, L. Rajngewerc, T. Tran, K. Phan, M. S. Ramirez, W. Reisner, M. E. Tolmasky, R. Reyes-Lamothe. Dynamics and quantitative contribution of the aminoglycoside 6'-N-acetyltransferase type Ib to amikacin resistance. mSphere 2024 3 e00789-23. doi: 10.1128/msphere.00789-23
171. G. Traglia, M. S. Ramírez, M. E. Tolmasky. Role of Xer site-specific recombination in the genesis of pJHCMW1: an evolutionary hypothesis. Journal of Global Antimicrobial Resistance 2023. doi: 10.1016/j.jgar.2023.07.017
170. B. Nishimura, J. Escalante, V. Mezcord, M. Tuttobene, T. Subils, L. A. Actis, F. Pasteran, M. E. Tolmasky, R. A. Bonomo, M. S. Ramirez. Human serum albumin-induced modification of Ton-B-dependent receptor expression in cefiderocol-exposed carbapenem-resistant Acinetobacter baumannii. International Journal of Antimicrobial Agents 2023 62 106950. doi: 10.1016/j.ijantimicag.2023.106950
169. A. J. Magaña, J. Sklenicka, C. Pinilla, M. Giulianotti, P. Chapagain, R. Santos, M. S. Ramirez, M. E. Tolmasky. Restoring susceptibility to aminoglycosides: identifying small molecule inhibitors of enzymatic inactivation. RSC Medicinal Chemistry 2023. doi: 10.1039/D3MD00226H
168. V. Mezcord, J. Escalante, B. Nishimura, G. Traglia, R. Sharma, Q. Valle, M. Tuttobene, T. Subils, I. Marin, F. Pasterán, L. A. Actis, M. E. Tolmasky, R. A. Bonomo, G. Rao, M. S. Ramírez. Induced heteroresistance in carbapenem-resistant Acinetobacter baumannii (CRAB) via exposure to human pleural fluid (HPF) and its impact on cefiderocol susceptibiity. International Journal of Molecular Sciences 2023. doi: 10.3390/ijms241411752
167. M. E. Tolmasky. Plasmids. Reference Module in Life Sciences 2023 doi: 10.1016/B978-0-12-822563-9.00084-6
166. G. Traglia, F. Pasteran, J. Escalante, B. Nishimura, M. Tuttobene, T. Subils, M. Nuñez, M. Rivollier, A. Corso, M. E. Tolmasky, M. S. Ramirez. Genomic comparative analysis of two multi-drug resistance (MDR) Acinetobacter baumannii clinical strains assigned to international clonal lineage II recovered pre- and post-COVID-19 pandemic. Biology 2023 12 358. doi: 10.3390/biology12030358
165. J. Escalante, B. Nishimura, M. Tuttobene, T. Subils, V. Mezcord, L. A. Actis, M. E. Tolmasky, R. A. Bonomo, M. S. Ramirez. The iron content of human serum albumin modulates the susceptibility of Acinetobacter baumannii to cefiderocol. Biomedicines 2023 11 639. doi: 10.3390/biomedicines11020639
164. D. Ngo, A. J. Magaña, T. Tran, J. Sklenicka, K. Phan, B. Ekholt, V. Jimenez, M. S. Ramirez, and M. E. Tolmasky. Inhibition of enzymatic acetylation-mediated resistance to plazomicin by silver ions. Pharmaceuticals 2023 16 236. doi: 10.3390/ph16020236
163. V. Mezcord, O. Wong, F. Pasteran, A. Corso, C, M. E. Tolmasky, R. A. Bonomo, and M. S. Ramirez. Role of β-lactamase inhibitors on cefiderocol activity against carbapenem-resistant Acinetobacter species. International Journal of Antimicrobial Agents 2023 61 106700. doi: 10.1016/j.ijantimicag.2022.106700
162. J. Escalante, B. Nishimura, M. Tuttobene, T. Subils, C. Pimentel, N. Georgeos, R. Sieira, R. A. Bonomo, M. E. Tolmasky, and M. S. Ramirez. Human serum albumin (HSA) regulates the expression of histone-like nucleoid structure protein (H-NS) in Acinetobacter baumannii. Scientific Reports 2022 12 14644. doi: 10.1038/s41598-022-19012-y
161. J. Cedano, M. Baez, F. Pasteran, S. Montaña, G. Ra, V. Fua, A. Corso, M. E. Tolmasky, R. A. Bonomo, and M. S. Ramirez. Zidebactam restores sulbactam susceptibility against carbapenem-resistant Acinetobacter baumannii isolates. Frontiers in Cellular anf Infection Microbiology 2022 12 918868. doi: 10.3389/fcimb.2022.918868
160. B. Nishimura, J. Escalante, M. Tuttobene, T. Subils, V. Mezcord, C. Pimentel, N. Georgeos, F. Pasteran, C. Rodriguez, L. A. Actis, M. E. Tolmasky, R. A. Bonomo, and M. S. Ramirez. Acinetobacter baumannii response to cefiderocol challenge in human urine. Scientific Reports 2022 12 8763. doi: 10.1038/s41598-022-12829-7
159. C. Le, C. Pimentel, F. Pasteran, M. Tuttobene, T. Subils, J. Escalante, B. Nishimura, S. Arriaga, A. Carranza, V. Mezcord, A. Vila, A. Corso, L. A. Actis, M. E. Tolmasky, R. A. Bonomo, and M. S. Ramirez. Human serum proteins and susceptibility of Acinetobacter baumannii to cefiderocol: role of iron transport. Biomedicines 2022 10 600. doi: 10.3390/biomedicines10030600
158. J. Magallon, P. Vu, C. Reeves, S. Kwan, K. Phan, C. Oakley-Havens, K. Rocha, V. Jimenez, M. S. Ramirez, and M. E. Tolmasky. Amikacin potentiator activity of zinc complexed to a pyrithione derivative with enhanced solubility. Scientific Reports 2022 12 285. doi:10.1038/s41598-021-04724-4
157. J. Magallon, P. Vu, C. Reeves, S. Kwan, K. Phan, C. Oakley-Havens, M. S. Ramirez, and M. E. Tolmasky. Amikacin in combination with zinc pyrithione prevents growth of a carbapenem-resistant/multidrug-resistant Klebsiella pneumoniae isolate. International Journal of Antimicrobial Agents 2021 106442. doi:10.1016/j.ijantimicag.2021.106442
156. C. Le, C. Pimentel, M. Tuttobene, T. Subils, K. Papp-Wallace, R. A. Bonomo, L. Actis, M. E. Tolmasky, and M. S. Ramirez. Effect of serum albumin, a component of human pleural fluid, on transcriptional and phenotypic changes on Acinetobacter baumanniiA118. Current Microbiology 2021 78 3829–3834. doi: 10.1007/s00284-021-02649-9
155. K. Rocha, J. Magallon, C. Reeves, K. Phan, P. Vu, C. Oakley-Havens, S. Kwan, M. S. Ramirez, T. LaVoi, H. Donow, P. Chapagain, R. Santos, C. Pinilla, M. Giulianotti, and M. E. Tolmasky. Inhibition of aminoglycoside 6'-N-acetyltransferase type Ib [AAC(6′)-Ib]: structure-activity relationship of substituted pyrrolidine pentamine derivatives as inhibitors. Biomedicines 2021 9 1218. doi: 10.3390/biomedicines9091218
154. D. Rodgers, C. Le, C. Pimentel, M. Tuttobene, T. Subils, J. Escalante, B. Nishimura, E. Vescovi, R. Sierra, R. A. Bonomo, M. E. Tolmasky, and M. S. Ramirez. Histone-like nucleoid-structuring protein (H-NS) regulatory role in antibiotic resistance in Acinetobacter baumannii. Scientific Reports 2021 11 18414. doi: 10.1038/s41598-021-98101-w
153. C. Le, C. Pimentel, M. Tuttobene, T. Subils, J. Escalante, B. Nishimura, S. Arriaga, D. Rodgers, R. A. Bonomo, R. Sieira, M. E. Tolmasky, and M. S. Ramirez. Involvement of H-NS in Acinetobacter baumannii’s natural transformation. Pathogens 2021 10 1083. doi: 10.3390/pathogens10091083
152. C. Le, C. Pimentel, M. Tuttobene, T. Subils, B. Nishimura, G. M. Traglia, F. Perez, K. Papp-Wallace, R. A. Bonomo, M. E. Tolmasky, and M. S. Ramirez. Interplay between meropenem and human serum albumin on expression of carbapenem resistance genes and natural competence in Acinetobacter baumannii. Antimicrobial Agents and Chemotherapy 2021. doi: 10.1128/AAC.01019-21
151. C. Pimentel, C. Le, M. Tuttobene, T. Subils, K. Papp-Wallace, R. A. Bonomo, M. E. Tolmasky, and M. S. Ramirez. Interaction of Acinetobacter baumannii with human serum albumin: does the host determine the outcome? Antibiotics 2021 10 833. doi: 10.3390/antibiotics10070833
150. F. Pasteran, J. Cedano, M. Baez, E. Albornoz, M. Rapoport, J. Osteria, S. Montaña, C. Le, G. Ra, R. A. Bonomo, M. E. Tolmasky, M. Adams, A. Corso, and M. S. Ramirez. A new twist: the combination of sulbactam/avibactam enhances sulbactam activity against carbapenem-resistant Acinetobacter baumannii (CRAB) isolates. Antibiotics 2021 10 577. doi: 10.3390/antibiotics10050577
149. S. Jani, M. S. Ramirez, and M. E. Tolmasky. Silencing antibiotic resistance with antisense oligonucleotides. Biomedicines 2021 9 416. doi: 10.3390/biomedicines9040416
148. C. Pimentel, C. Le, M. Tuttobene, T. Subils, J. Martinez, R. Sieira, K. Papp-Wallace, N. Keppetipola, R. A. Bonomo, L. A. Actis, M. E. Tolmasky, M. S. Ramirez. Human pleural fluid and human serum albumin modulate the behavior of a hypervirulent and multidrug-resistant (MDR) Acinetobacter baumannii representative strain. Pathogens 2021 10 471. doi: 10.3390/pathogens10040471
147. M. Cuajungco, M. S. Ramirez, and M. E. Tolmasky. Zinc: multidimensional effects on living organisms. Biomedicines 2021 9 208. doi: 10.3390/biomedicines9020208
146. J. Martinez, C. Razo-gutierrez, C. Le, R. Courville, C. Pimentel, C. Liu, S. Fung, M. Tuttobene, K. Phan, A. Vila, P. Sharestani, V. Jimenez, M. E. Tolmasky, S. Becka, K. Papp-Wallace, R. A. Bonomo, A. Soler-Bistue, R. Sieira, and M. S. Ramirez. Cerebrospinal fluid (CSF) augments metabolism and virulence expression factors in Acinetobacter baumannii. Scientific Reports 2021 11 4737. doi: 10.1038/s41598-021-81714-6
145. C. Reeves, J. Magallon, K. Rocha, T. Tran, K. Phan, P. Vu, Y. Yi, C. L. Oakley-Havens, J. Cedano, V. Jimenez, M. S. Ramirez, and M. E. Tolmasky. Aminoglycoside 6'-N-acetyltransferase type Ib [AAC(6')-Ib]-mediated aminoglycoside resistance: phenotypic conversion to susceptibility by silver ions. Antibiotics 2021 10 29. doi: 10.3390/antibiotics10010029
144. A. Baraka, G. M. Traglia, S. Montaña, M. E. Tolmasky, and M. S. Ramirez. An Acinetobacter non-baumannii population study: antimicrobial resistance genes (ARGs). Antibiotics 2021 10 16. doi: 10.3390/antibiotics10010016
143. D. L. Lin, G. M. Traglia, R. Baker, D. J. Sherratt, M. S. Ramirez, and M. E. Tolmasky. Functional analysis of the Acinetobacter baumannii XerC and XerD site-specific recombinases: potential role in dissemination of resistance genes. Antibiotics 2020 9 405. doi: 10.3390/antibiotics9070405
142. M. S. Ramirez, R. A. Bonomo, and M. E. Tolmasky. Carbapenemases: transforming Acinetobacter baumannii into a yet more dangerous menace. Biomolecules 2020 10 720. doi: 10.3390/biom10050720
141. J. Martinez, J. Fernandez, C. Liu, A. Hoard, A. Mendoza, J. Nakanouchi, N. Rodman, R. Courville, M. Tuttobene, C. Lopez, L. Gonzalez, P. Sharestani, K. Papp-Wallace, A. Vila, M. E. Tolmasky, R. A. Bonomo, R. Seira, and M. S. Ramirez. Human pleural fluid triggers global changes in the transcriptional landscape of Acinetobacter baumannii as an adaptive response to stress. Scientific Reports 2019 9 17251. doi: 10.1038/s41598-019-53847-2
140. V. Batallones, J. Fernandez, B. Farthing, J. Shoemaker, K. L. Qian, K. Phan, E. Fung, A. Rivera, K. Van, F. de la Cruz, A. J. Ferreri, K. Burinski, J. Zhang, V. Lizarraga, K. Doan, K. Rocha, G. Traglia, M. S. Ramirez, and M. E. Tolmasky. Disruption of hmgA by DNA duplication is responsible for hyperpigmentation in a Vibrio anguillarum strain. Scientific Reports 2019 9 14589. doi: 10.1038/s41598-019-51126-8
139. R. K. Moise, K. Srithanaviboonchai, A. Alsolami, B. R. Elewonibi, M. E. Tolmasky, and M. M. Wood. The patient–provider continuum of care: narratives of people living with comorbid HIV and diabetes in Northern Thailand. Journal of Patient Experience 2019. doi: 10.1177/2374373519882226
138. M. S. Ramirez, A. Iriarte, R. Reyes-Lamothe, D. J. Sherratt, and M. E. Tolmasky. Small Klebsiella pneumoniae plasmids: neglected contributors to antibiotic resistance. Frontiers in Microbiology 2019 10 2182. doi: 10.3389/fmicb.2019.02182
137. M. S. Ramirez, W. F. Penwell, G. M. Traglia, D. L. Zimbler, J. A. Gaddy, N. Nikolaidis, B. A. Arivett, M. D. Adams, R. A. Bonomo, L. A. Actis, and M. E. Tolmasky. Identification of potential virulence factors in the model strain Acinetobacter baumannii A118. Frontiers in Microbiology 2019 10 1599. doi: 10.3389/fmicb.2019.01599
136. A. Soler Bistué, A. Zorreguieta, and M. E. Tolmasky. Bridged nucleic acids reloaded. Molecules 2019 24 2297. doi:10.3390/molecules24122297
135. J. Magallon, K. Chiem, T. Tran, M. S. Ramirez, V. Jimenez, and M. E. Tolmasky. Restoration of susceptibility to amikacin by 8-hydroxyquinoline analogs complexed to zinc. PLOS ONE 2019 14 e0217602. doi: 10.1371/journal.pone.0217602
134. G. M. Traglia, K. Place, C. Dotto, J. S. Fernandez, S. Montaña, C. dos Santos Bahiense, A. Soler Bistué, A. Iriarte, F. Perez, M. E. Tolmasky, R. A. Bonomo, R. Melano, and M. S. Ramirez. Interspecies DNA acquisition by a naturally competent Acinetobacter baumannii strain. International Journal of Antimicrobial Agents 2019 53 483-490. doi: 10.1016/j.ijantimicag.2018.12.013
133. G. M. Traglia, K. Chiem, B. Quinn, J. S. Fernandez, S. Montaña, M. Almuzara, M. Mussi, M. E. Tolmasky, A. Iriarte, D. Centrón, and M. S. Ramirez. Genome sequence analysis of an extensively drug-resistant Acinetobacter baumannii indigo-pigmented strain depicts evidence of increase genome plasticity. Scientific Reports 2018 8 16961. doi: 10.1038/s41598-018-35377-5
132. C. Davies Sala, S. Jani, A. Zorreguieta, and M. E. Tolmasky. Identification of the Acinetobacter baumannii Ribonuclease P catalytic subunit: cleavage of a target mRNA in the presence of an external guide sequence. Frontiers in Microbiology 2018 9 2408. doi: 10.3389/fmicb.2018.02408
131. T. Tran, K. Chiem, S. Jani, B. A. Arivett, D. L. Lin, R. Lad, V. Jimenez, M. B. Farone, G. Debevec, R. Santos, M. Giulianotti, C. Pinilla, and M. E. Tolmasky. Identification of a small molecule inhibitor of the aminoglycoside 6'-N-acetyltransferase type Ib [AAC(6')-Ib] using mixture-based combinatorial libraries. International Journal of Antimicrobial Agents 2018 51 752-761. doi: 10.1016/j.ijantimicag.2018.01.019
130. C. Collins, M. Almuzara, M. Saigo, S. Montaña, K. Chiem, G. Traglia, M. A. Mussi, M. E. Tolmasky, A. Iriarte, C. Vay, and M. S. Ramirez. Whole-genome analysis of an extensively drug-resistant Empedobacter falsenii strain reveals distinct features and the presence of a novel metallo-beta-lactamase (EBR-2). Current Microbiology 2018 75 1084-1089. doi: doi.org/10.1007/s00284-018-1498-9
129. S. Jani, A. Jackson, C. Davies Sala, A. Soler-Bistué, A. Zorreguieta, and M. E. Tolmasky. Assessment of external guide sequences’ (EGS) efficiency as inducers of RNase P-mediated cleavage of mRNA target molecules. Methods in Molecular Biology 2018 1737 89-98. doi: 10.1007/978-1-4939-7634-8_6
128. K. Chiem, F. Hue, J. Magallon, and M. E. Tolmasky. Inhibition of aminoglycoside 6'-N-acetyltransferase type Ib-mediated amikacin resistance by zinc complexed to clioquinol, an ionophore active against tumors and neurodegenerative diseases. International Journal of Antimicrobial Agents 2018 51 271-273. doi: 10.1016/j.ijantimicag.2017.08.002
127. M. S. Ramirez and M. E. Tolmasky. Amikacin: uses, resistance, and prospects for inhibition. Molecules 2017 22 2267. doi: 10.3390/molecules22122267
126. M. S. Stietz, C. Lopez, O. Osifo, M. E. Tolmasky, and S. T. Cardona. Evaluation of the electron transfer flavoprotein (ETF) as an antibacterial target in Burkholderia cenocepacia. Canadian Journal of Microbiology (2017) 63 857-863. doi: 10.1139/cjm-2017-0350. PMID: 28817787
125. M. E. Tolmasky. Strategies to prolong the useful life of existing antibiotics and help overcoming the antibiotic resistance crisis. In Frontiers in Clinical Drug Research-Anti Infectives, (Atta-ur-Rahman, ed.) 2017, vol 4, 1-27. Bentham Science Publishers.
124. M. E. Tolmasky. Plasmids. In Reference Module in Life Sciences (2017). Elsevier Ltd, Oxford, UK. doi: 10.1016/B978-0-12-809633-8.06917-X
123. A. Jackson, S. Jani, C. Davies Sala, A. Soler-Bistué, A. Zorreguieta, and M. E. Tolmasky. Assessment of configurations and chemistries of bridged nucleic acids-containing oligomers as external guide sequences: a methodology for inhibition of expression of antibiotic resistance genes. Biology Methods & Protocols 2016 1(1):bpw001. doi: 10.1093/biomethods/bpw001. PMID: 27857983, PMCID: PMC5108630
122. S. Montaña, S. T. J. Schramm, G. M. Traglia, K. Chiem, G. Parmeciano Di Noto, M. Almuzara, C. Barberis, C. Vay, C. Quiroga, M. E. Tolmasky, A. Iriarte, M. S. Ramírez. The genetic analysis of an Acinetobacter johnsonii clinical strain evidenced the presence of horizontal genetic transfer. PLOS ONE 2016 11(8): e0161528. doi: 10.1371/journal.pone.0161528. PMID: 27548264
121. M. S. Ramirez, G. Xie, G. M. Traglia, S. Johnson, K. Davenport, D. van Duin, A. Ramazani, F. Perez, M. R. Jacobs, D. J. Sherratt, R. A. Bonomo, P. Chain, and M. E. Tolmasky. Whole-genome comparative analysis of two carbapenem-resistant ST-258 Klebsiella pneumoniae strains isolated during a North-Eastern Ohio outbreak: differences within the High Heterogeneity Zones. Genome Biology and Evolution 2016 8 2036-2043. doi: 10.1093/gbe/evw135. PMID: 27289094, PMCID: PMC4943203
120. K. Chiem, S. Jani, B. Fuentes, D. L. Lin, M. E. Rasche, and M. E. Tolmasky. Identification of an inhibitor of the aminoglycoside 6’-N-acetyltransferase type Ib [AAC(6′)-Ib] by Glide molecular docking. MedChemComm 2016 7 184-189. doi: 10.1039/c5md00316d. PMID: 26973774, PMCID: PMC4784703
119. K. Chiem, B. Fuentes, D. L. Lin, T. Tran, A. Jackson, M. S,. Ramirez, and M. E. Tolmasky. Inhibition of of aminoglycoside 6'-N-acetyltransferase type Ib-mediated amikacin resistance in Klebsiella pneumoniae by zinc and copper pyrithione. Antimicrobial Agents and Chemotherapy 2015 59 5851-5853. doi: 10.1128/AAC.01106-15. PMID: 26169410, PMCID: PMC4538519
118. C. Lopez, B. Arivett, L. A. Actis, and M. E. Tolmasky. Inhibition of AAC(6')-Ib-mediated resistance to amikacin in Acinetobacter baumannii by an antisense peptide-conjugated 2',4'-bridged nucleic acid-NC-DNA hybrid oligomer. Antimicrobial Agents and Chemotherapy 2015 59 5798-5803. doi: 10.1128/AAC.01304-15. PMID: 26169414, PMCID: PMC4538503
117. C. Davies Sala, A. J. C. Soler Bistué, R. A. Bonomo, A. Zorreguieta, and M. E. Tolmasky. External Guide Sequence (EGS) technology: a path to development of novel antimicrobial therapeutics. Annals of the New York Academy of Sciences 2015 1354 98-110. doi: 10.1111/nyas.12755. PMID: 25866265, PMCID: PMC4600001
116. G. Traglia, C. Dixon, K. Chiem, M. Almuzara, C. Barberis, S. Montaña, C. Merino, M. Mussi, M. E. Tolmasky, A. Iriarte, C. Vay, and M. S. Ramirez. Draft Genome Sequence of Empedobacter falsenii comb. nov. (ex-Wautersiella falsenii) Wf282, a strain isolated from a cervical neck abscess. Genome Announcements 2015 3 e00235-15. doi: 10.1128/genomeA.00235-15. PMID: 25838490, PMCID: PMC4384494
115. J. Lin, K. Nishino, M. Roberts, D. Centron, M. E. Tolmasky, R. Aminov, and L. Zhang. Mechanisms of antibiotic resistance. Frontiers in Microbiology 2015 6 34. doi: 10.3389/fmicb.2015.00034. PMID: 25699027
114. B. Arivett, S. Fiester, D. Ream, D. Centron, M. S. Ramirez, M. E. Tolmasky, and L. A. Actis. Draft genome of the multidrug-resistant Acinetobacter baumannii A155 clinical isolate. Genome Announcements 2015 3 e00212-15. doi: 10.1128/genomeA.00212-15. PMID: 25814610, PMCID: PMC4384150
113. M. S. Ramirez, G. M. Traglia, D. L. Lin, T. Tran, and M. E. Tolmasky. Plasmid-mediated antibiotic resistance and virulence in Gram-negatives: the Klebsiella pneumoniae paradigm. Microbiology Spectrum 2014 2 PLAS-0016-2013 doi:10.1128/microbiolspec.PLAS-0016-2013
112. G. M. Traglia, K. Chua, D. Centrón, M. E. Tolmasky, and M. S. Ramirez. Whole genome sequence analysis of the naturally competent Acinetobacter baumannii clinical isolate A118. Genome Biology and Evolution 2014 6 2235-2239. doi: 10.1093/gbe/evu176. PMID: 25164683, PMCID: PMC4202317
111. M. S. Ramirez, G. Xie, S. Johnson, K. Davenport, D. van Duin, F. Perez, R. A. Bonomo, P. Chain, and M. E. Tolmasky. Genome sequences of two carbapenemase-resistant Klebsiella pneumoniae ST258 isolates. Genome Announcements 2014 2 e00558-14. doi: 10.1128/genomeA.00558-14. PMCID: PMC4064024
110. D. L. Lin, T. Tran, J. Y. Alam, S. Herron, M. S. Ramirez, and M. E. Tolmasky. Inhibition of aminoglycoside 6'-N-acetyltransferase type Ib by zinc: reversal of amikacin resistance in Acinetobacter baumannii and Escherichia coli by a zinc ionophore. Antimicrobial Agents and Chemotherapy 2014 58 4238-4241. doi: 10.1128/AAC.00129-14. PMCID: PMC4068593
109. R. Reyes-Lamothe, T. Tran, D. Meas, L. Lee, A. Li, D. Sherratt, and M. E. Tolmasky. High-copy bacterial plasmids diffuse in the nucleoid-free space, replicate stochastically, and are randomly partitioned at cell division. Nucleic Acids Research 2014 42 1042-1051. doi: 10.1093/nar/gkt918. PMCID: PMC3902917
108. D. L. Lin, T. Tran, C. Adams, J. Y. Alam, S. Herron, and M. E. Tolmasky. Inhibitors of the aminoglycoside 6'-N-acetyltransferase type Ib [AAC(6')-Ib] identified by in silico molecular docking. Bioorganic & Medicinal Chemistry Letters 2013 23 5694-5698. doi: 10.1016/j.bmcl.2013.08.016. PMID: 24011645, PMCID: PMC3821527
107. D. L. Lin, M. S. Ramirez, T. Tran, and M. E. Tolmasky. A cointegrate-like plasmid that facilitates dissemination by conjugation of the extended-spectrum beta-lactamase CTX-M-17. Antimicrobial Agents and Chemotherapy 2013 57 5191-5192. doi: 10.1128/AAC.01365-13. PMID: 23877684, PMCID: PMC3811462
106. M. S. Ramirez, N. Nikolaidis, and M. E. Tolmasky. Rise and dissemination of aminoglycoside resistance: the aac(6')-Ib paradigm. Frontiers in Microbiology 2013 4 121. doi: 10.3389/fmicb.2013.00121. PMID: 23730301, PMCID: PMC3656343
105. P. Andres, C. Lucero, A. J. C. Soler Bistué, L. Guerriero, E. Albornoz, T. Tran, A. Zorreguieta, M. Galas, A. Corso, M. E. Tolmasky, and A. Petroni. Differential distribution of plasmid mediated quinolone resistance genes in clinical enterobacteria with unusual phenotypes of quinolone susceptibility from Argentina. Antimicrobial Agents and Chemotherapy 2013 57 2467-2475. doi: 10.1128/AAC.01615-12. PMID: 23478955, PMCID: PMC3716127
104. M. E. Tolmasky. Plasmids. In Brenner's Encyclopedia of Genetics, 2nd Edition, (S. Maloy, S. and Hughes, K., Eds.), 2013 362-366
103. G. Xie, M. S. Ramirez, S. Marshall, K. Hujer, C. Lo, S. Johnson, P. Li, K. Davenport, A. Endimiani, R. A. Bonomo, M. E. Tolmasky, and P. Chain. Genome sequences of two Klebsiella pneumoniae isolates from different geographical regions: Argentina (JHCK1) and the United States (VA360). Genome Announcements 2013 1 e00168-13. doi: 10.1128/genomeA.00168-13. PMID: 23640195, PMCID: PMC3642250
102. C. Davies Sala, A. J. C. Soler Bistué, L. Korprapun, A. Zorreguieta, and M. E. Tolmasky. Inhibition of cell division induced by external guide sequences (EGS technology) targeting ftsZ. PLOS ONE 2012 7 e47690. doi: 10.1371/journal.pone.0047690. PMID: 23110089
101. G. M. Traglia, C. Davies Sala, J. I. Fuxman Bass, A. J. C. Soler Bistué, A. Zorreguieta, M. S. Ramirez, and M. E. Tolmasky. Internalization of locked nucleic acids/DNA hybrid oligomers into Escherichia coli. BioResearch Open Access 2012 1 260-263. doi: 10.1089/biores.2012.0257. PMID: 23515318
100. M. S. Ramirez, G. Xie, S. H. Marshall, K. H. Hujer, P. S. Chain, R. A. Bonomo, and M. E. Tolmasky. Multidrug resistance (MDR) Klebsiella pneumoniae clinical isolates: a zone of high heterogeneity (HHZ) as a tool for epidemiological studies. Clinical Microbiology and Infection 2012 18 E254-E258. doi: 10.1111/j.1469-0691.2012.03886.x. PMID: 22551038
99. T. Tran, P. Andres, A. Petroni, A. J. C. Soler Bistué, E. Albornoz, A. Zorreguieta, R. Reyes-Lamothe, D. J. Sherratt, A. Corso, and M. E. Tolmasky. Small plasmids harboring qnrB19: a model for plasmid evolution mediated by site-specific recombination at oriT and Xer sites. Antimicrobial Agents and Chemotherapy 2012 56 1821-1827. PMID: 22290975
98. H. Naka, Q. Chen, Y. Mitoma, Y. Nakamura, D. McIntosh-Tolle, A. Gammie, M. E. Tolmasky, and J. H. Crosa. Two replication regions in the pJM1 virulence plasmid of the marine pathogen Vibrio anguillarum. Plasmid 2012 67 95-101. PMID: 22239981
97. G. Warburg, C. Hidalgo-Grass, S. R. Partridge, M. E. Tolmasky, V. Temper, A. E. Moses, C. Block, and J. Strahilevitz. A carbapenem-resistant Klebsiella pneumoniae epidemic clone in Jerusalem: sequence type 512 carrying a plasmid encoding aac(6')-Ib . Journal of Antimicrobial Chemotherapy 2012 67 898-901. PMID: 22287232
96. P. S. Chain, D. M. Lang, D. J. Comerci, S. A. Malfatti, L. M. Vergez, M. Shin, R. A. Ugalde, E. Garcia, and M. E. Tolmasky. Genome of Ochrobactrum anthropi ATCC 49188T, a versatile opportunistic pathogen and symbiont of several eukaryotic hosts. Journal of Bacteriology 2011 193 4274-4275. PMID: 21685287
95. M. S. Ramirez, M. D. Adams, R. A. Bonomo, D. Centron, and M. E. Tolmasky. Genomic Analysis of Acinetobacter baumannii A118 by Comparison of Optical Maps: Identification of Structures Related to its Susceptibility Phenotype. Antimicrobial Agents and Chemotherapy 2011 55 1520-1526. PMID: 21282446
94. L. A. Actis, M. E. Tolmasky, and J. H. Crosa. Vibriosis. In Fish Diseases and Disorders, vol. 3: Viral, Bacterial, and Fungal Infections, 2nd edition, (Woo, P. T. K. and Bruno, D. W., Eds.), 2011, pp. 570-605. CABI International, Wallingford, Oxfordshire OX10 8DE, England.
93. M. S. Ramirez and M. E. Tolmasky. Aminoglycoside modifying enzymes. Drug Resistance Updates 2010 13 151-171. PMID: 20833577
92. M. S. Ramirez, M. Don, A. K. Merkier, A. J. C. Soler Bistué, A. Zorreguieta, D. Centrón, and M. E. Tolmasky. Naturally competent Acinetobacter baumannii clinical isolate as a convenient model for genetic studies. Journal of Clinical Microbiology 2010 48 1488-1490. PMID: 20181905
91. T. Tran, D. J. Sherratt, and M. E. Tolmasky. fpr, a deficient Xer recombination site from a Salmonella plasmid fails to confer stability by dimer resolution: comparative studies with the pJHCMW1 mwr site. Journal of Bacteriology 2010 192 883-887. PMID: 19966005
90. J. C. Alonso, and M. E. Tolmasky. Enzybiotics as selective killers of target bacteria. In Enzybiotics: Antibiotic Enzymes as Drugs and Therapeutics, (Villa, T. G. and Veiga-Crespo, P., Eds.), 2010, pp. 59-74. John Wiley and Sons, Inc., Hoboken, New Jersey.
89. M. E. Tolmasky, L. A. Actis, and J. H. Crosa. Plasmid DNA replication. In Encyclopedia of Industrial Biotechnology: Bioprocess, Bioseparation, and Cell Technology, (Flickinger, M., Ed.), 2010, vol 6, pp. 3931-3953. John Wiley and Sons, Inc., New York, NY. Published online: 15 APR 2010, DOI: 10.1002/9780470054581.eib487
88. A. J. C. Soler Bistué, F. Martín, N. Vozza, H Ha, J. Joaquín, A. Zorreguieta, and M. E. Tolmasky. Inhibition of aac(6')-Ib-mediated amikacin resistance by nuclease resistant external guide sequences in bacteria. Proceedings of the National Academy of Sciences of USA 2009 106 13230-13235
87. S. Trigueros, T. Tran, N. Sorto, J. Newmark, S. Colloms, D. J. Sherratt, and M. E. Tolmasky. mwr Xer site-specific recombination is hypersensitive to DNA supercoiling. Nucleic Acids Research 2009 37 3580-358786. M. S. Ramirez, T. R. Parenteau, D. Centrón, and M. E. Tolmasky. Functional Characterization of Tn1331 Gene Cassettes. Journal of Antimicrobial Chemotherapy 2008 62 669-673
85. M. Di Lorenzo, M. Stork, H. Naka, M. E. Tolmasky, and J. H. Crosa. Tandem heterocyclization domains in a nonribosomal peptide synthetase essential for siderophore biosynthesis in Vibrio anguillarum. BioMetals 2008 21 635-648
84. A. J. C. Soler Bistué, D. Birshan, A. P. Tomaras, M. Dandekar, T. Tran, J. Newmark, D. Bui, N. Gupta, K. Hernandez, R. Sarno, A. Zorreguieta, L. A. Actis, and M. E. Tolmasky. Klebsiella pneumoniae multiresistance plasmid pMET1: similarity with the Yersinia pestis plasmid pCRY and integrative conjugative elements. PLOS ONE 2008 3 e1800
83. M. P. Quiroga, P. Andrés, A. Petroni, A. J. C. Soler-Bistué, L. Guerriero, L. Jordá Vargas, A. Zorreguieta, M. Tokumoto, C. Quiroga, M.E. Tolmasky, M. Galas, and D. Centrón. Complex class 1 integrons with diverse variable regions including aac(6’)-Ib-cr and a novel allele qnrB10 associated to ISCR1 in clinical enterobacteria from Argentina. Antimicrobial Agents and Chemotherapy 2007 51 4466-4470
82. M. E. Tolmasky, L. A. Actis, T. Welch, and J. H. Crosa. Plasmids. In Methods for General and Molecular Microbiology, (Reddy, C. A., Beveridge, T. J., Breznak, J. A., Marzluf, G., Schmidt, T. M., Snyder, L. R., Eds.), 2007, pp. 709-734 , American Society for Microbiology, Washington, DC.
81. A. J. C. Soler Bistué, H. Ha, R. Sarno, M. Don, A. Zorreguieta, and M. E. Tolmasky. External guide sequences targeting the aac(6’)-Ib mRNA induce inhibition of amikacin resistance. Antimicrobial Agents and Chemotherapy 2007 51 1918-1925
80. C. Possoz, J. Newmark, N. Sorto, D. J. Sherratt, and M. E. Tolmasky. Sublethal Concentrations of the aminoglycoside amikacin interfere with cell division without affecting chromosome dynamics. Antimicrobial Agents and Chemotherapy 2007 51 252-256
79. M. E. Tolmasky. Overview of dissemination mechanisms of genes coding for resistance to antibiotics. In Enzyme-Mediated Resistance to Antibiotics: Mechanisms, Dissemination, and Prospects for Inhibition, (R. A. Bonomo and M. E. Tolmasky, Eds.), 2007, pp. 265-268, American Society for Microbiology, Washington, DC.
78. M. E. Tolmasky. Aminoglycoside-modifying enzymes: characteristics, localization, and dissemination. In Enzyme-Mediated Resistance to Antibiotics: Mechanisms, Dissemination, and Prospects for Inhibition, (R. A. Bonomo and M. E. Tolmasky, Eds.), 2007, pp. 35-52, American Society for Microbiology, Washington, DC.
77. A. J. C. Soler Bistué, F. A. Martin, A. Petroni, D. Faccone, M. Galas, M. E. Tolmasky, and A. Zorreguieta. Vibrio cholerae InV117, a class 1 integron harboring aac(6')-Ib and blaCTX-M-2, is linked to transposition genes. Antimicrobial Agents and Chemotherapy 2006 50 1903-1907
76. J. H. Crosa, L. A. Actis, and M. E. Tolmasky. The biology and pathogenicity of Vibrio anguillarum and V. ordalii. In The Biology of Vibrios, (F. L. Thompson et al., Eds.), 2006, pp. 253-266, American Society for Microbiology, Washington, DC.
75. D. Bui, J. Ramiscal, S. Trigueros, J. Newmark, A. Do, D. Sherratt, and M. E. Tolmasky. Differences in resolution of mwr-containing plasmid dimers mediated by the Klebsiella pneumoniae and Escherichia coli XerC recombinases: potential implications in dissemination of antibiotic resistance genes. Journal of Bacteriology 2006 188 2812-2820
74. P. Chain, D. Comerci, M. E. Tolmasky, F. Larimer, S. Malfatti, L. Vergez, F. Aguero, M. Land, R. Ugalde, and E. Garcia. Whole-genome analyses of the speciation events in the pathogenic brucellae. Infection and Immunity 2005 73 8353-8361
73. A Pourreza, M. Witherspoon, J. Fox, J. Newmark, D. Bui, and M. E. Tolmasky. Mutagenesis analysis of a conserved region involved in acetyl coenzyme A binding in the aminoglycoside 6'-N-acetyltransferase type Ib encoded by the plasmid pJHCMW1. Antimicrobial Agents and Chemotherapy 2005 49 2979-2982
72. M. Di Lorenzo, S. Poppelaars, M. Nagasawa, M. Stork, M. E. Tolmasky, and J. H. Crosa. A nonribosomal peptide synthetase with a novel domain organization is essential for siderophore biosynthesis in Vibrio anguillarum. Journal of Bacteriology 2004 186 7327-7336
71. C. Dorsey, A. P. Tomaras, P. Connerly, M. E. Tolmasky, J. H. Crosa, and L. A. Actis. The siderophore-mediated iron acquisition systems of Acinetobacter baumannii 19606 and Vibrio anguillarum 775 are structurally and functionally related. Microbiology 2004 150 3657-3667
70. E. O'Rourke, A. V. Pinto, E. A. Petroni, M. E. Tolmasky, and L. Ielpi. Evidence for the active role of a novel nuclease from Helicobacter pylori in the horizontal transfer of genetic information. Journal of Bacteriology 2004 186 2586-2593
69. R. Sarno, H. Ha, N. Weinsetel, and M. E. Tolmasky. Inhibition of aminoglycoside 6'-Nacetyltransferase type Ib-mediated amikacin resistance by antisense oligodeoxynucleotides. Antimicrobial Agents and Chemotherapy 2003 47 3296-3304
68. M. Di Lorenzo, M. Stork, M. E. Tolmasky, L. Actis, D. Farrell, T. Welch, L. Crosa, A. Wertheimer, Q. Chen, P. Salinas, L. Waldbeser, and J. H. Crosa. Complete sequence of virulence plasmid pJM1 from the marine fish pathogen Vibrio anguillarum strain 775. Journal of Bacteriology 2003 185 5822-5830
67. K. Dery, B. Soballe, M. Witherspoon, D. Bui, R. Koch, D. Sherratt, and M. E. Tolmasky. The aminoglycoside 6'-N-acetyltransferase type Ib encoded by Tn1331 is evenly distributed within the cell's cytoplasm. Antimicrobial Agents and Chemotherapy 2003 47 2897-2902
66. C. W. Dorsey, M. E. Tolmasky, J. H. Crosa, and L. A. Actis. Genetic organization of an Acinetobacter baumannii chromosomal region harbouring genes related to siderophore biosynthesis and transport. Microbiology 2003 149 1227-1238
65. R. Sarno, G. McGillivary, D. Sherratt, L. A. Actis, and M. E.Tolmasky. Complete nucleotide sequence of Klebsiella pneumoniae multiresistance plasmid pJHCMW1. Antimicrobial Agents and Chemotherapy 2002 46 3422-3427
64. M. E. Tolmasky, L. A. Actis, and J. H. Crosa. Plasmid DNA replication. In The Encyclopedia of Bioprocess Technology: Fermentation, Biocatalisis and Bioseparation, (Flickinger, M., and Drew, S., Eds.), 2002. John Wiley and Sons, Inc., New York, NY.
63. H. Pham, K. Dery, D. Sherratt, and M. E.Tolmasky. Osmoregulation of dimer resolution at the plasmid pJHCMW1 mwr locus by Escherichia coli XerCD recombination. Journal of Bacteriology 2002 184 1607-1616
62. A. Shmara, N, Weinsetel , K. Dery, R. Chavideh , and M. E.Tolmasky. Systematic analysis of a conserved region of the aminoglycoside 6'-N-acetyltransferase type Ib. Antimicrobial Agents and Chemotherapy 2001 45 3287-3292
61. J. Echenique, C. Dorsey, L. Patrito, A. Petroni, M. E. Tolmasky, and L. Actis. Acinetobacter baumanii has two genes encoding gluthathione-dependent formaldehyde dehydrogenase: evidence for differential regulation in response to iron. Microbiology 2001 146: 581-589.
60. M. E. Tolmasky, S. Colloms, G. Blakely, and D. J. Sherratt. Stability by multimer resolution of pJHCMW1 is due to the Tn1331 resolvase and not to the Escherichia coli Xer system. Microbiology 2000 146: 581-589.
59. M. E. Tolmasky, L. A. Actis, and J. H. Crosa. Plasmid DNA replication. In The Encyclopedia of Bioprocess Technology: Fermentation, Biocatalisis and Bioseparation, (Flickinger, M., and Drew, S., Eds.), pp. 2004-2019, 1999. John Wiley and Sons, Inc., New York, NY.
58. A. Wertheimer, W. Verweij, Q. Chen, L. Crosa, M. Nagasawa, M. E.Tolmasky, L. Actis, and J. Crosa. Characterization of the angR gene of Vibrio anguillarum: essential role in virulence. Infection and Immunity 1999 67 6496-6509.
57. M. E.Tolmasky. Bacterial resistance to aminoglycosides and beta-lactams: the Tn1331 paradigm. Frontiers in Bioscience 1999 5 d20-d29. Special issue
56. R. Chavideh, S. Sholly, D. Panaite, and M. E. Tolmasky. Effect of F171 Mutations in the 6'-N-acetyltransferase type Ib [AAC(6')-Ib] enzyme on susceptibility to aminoglycosides. Antimicrobial Agents and Chemotherapy 1999 43 2811-2812.
55. L. Actis, M. E. Tolmasky, and J. H. Crosa. Bacterial plasmids: replication of extrachromosomal genetic elements encoding resistance to antimicrobial compounds. Frontiers in Bioscience 1999 3 43-62 Special issue
54. L. A. Actis, M. E. Tolmasky, and J. H. Crosa. Vibriosis. In Fish Diseases II: Bacterial and Fungal Infections, (Stevenson, R.M., and Woo, P.T., Eds.), 1999, pp. 523-557. CAB International, Wallingford, UK
53. N. Inon de Iannino, G. Briones, M. E. Tolmasky, and R. A. Ugalde. Molecular cloning and characterization of cgs, the Brucella abortus cyclic beta(1-2) glucan synthetase gene: genetic complementation of Rhizobium meliloti ndvB and Agrobacterium tumefaciens chvB mutants. Journal of Bacteriology 1998 180 4392-4400.
52. D. Bojorquez, M. Belei, S. F. DeLira, S. Sholly, J. Mead, and M. E. Tolmasky. Characterization of OXA-9, a beta-lactamase encoded by the multiresistance transposon Tn1331. Cellular and Molecular Biology 1998 44 483-491.
51. D. Panaite and M. E. Tolmasky. Characterization of mutants of the 6'-N-acetyltransferase encoded by the multiresistance transposon Tn1331: effect of Phe171Leu and Tyr80Cys substitutions. Plasmid 1998 39 123-133.
50. K. Dery, R. Chevideh, V. Waters, R. Chamorro, L. S. Tolmasky, M. E. Tolmasky. Characterization of the replication and mobilization regions of the multiresistance Klebsiella pneumoniae plasmid pJHCMW1. Plasmid 1997 38 97-105
49. Q. Chen, A. Wertheimer, M. E. Tolmasky, and J. H. Crosa. The AngR protein and the siderophore anguibactin positively regulate the expression of iron-transport genes in Vibrio anguillarum. Molecular Microbiology 1996 22 127-134.
48. M. E. Tolmasky, and J. H. Crosa. The multiresistance transposon Tn1331. In Recent Developments in Antimicrobial Agents & Chemotherapy, 1996, pp. 45-52. Scientific Information Guilld.
47. M. E. Tolmasky, and J. H. Crosa. Iron transport genes of the pJM1-mediated iron uptake system of Vibrio anguillarum are included in a transposonlike structure. Plasmid 1995 33 180-190.
46. L. A. Actis, M. E. Tolmasky, L. Crosa, and J. H. Crosa. Characterization and regulation of the expression of FatB, an iron transport protein encoded by the pJM1 virulence plasmid. Molecular Microbiology 1995 17 197-204.
45. M. E. Tolmasky, L. A. Actis, and J. H. Crosa. A histidine decarboxylase gene encoded by the Vibrio anguillarum plasmid pJM1 is essential for virulence: histamine is a precursor in the biosynthesis of anguibactin. Molecular Microbiology 1995 15 87-95.
44. A. Wertheimer, M. E. Tolmasky, L. A. Actis, and J. H. Crosa. Structural and functional analysis of mutant Fur proteins with impaired regulatory functions. Journal of Bacteriology 1994 176 5116-5122
43. Q. Chen, L.. A. Actis, M. E. Tolmasky, and J. H. Crosa. Chromosome-mediated 2,3-dihydroxybenzoic acid is a precursor in biosynthesis of the plasmid-mediated siderophore anguibactin in Vibrio anguillarum. Journal of Bacteriology 1994 176 4226-4234.
42. M. E. Tolmasky, A. Wertheimer, L. A. Actis, and J. H. Crosa. Characterization of the Vibrio anguillarum fur gene. Role in regulation of expression of the pJM1-mediated iron uptake system components.Journal of Bacteriology 1994 176 213-220.
41. J. H. Crosa, L. A. Actis, P. Salinas, M. E. Tolmasky, and L. Waldbeser. Regulation of the iron transport genes encoded by the pJM1 virulence plasmid in Vibrio anguillarum. In Molecular Mechanisms of Virulence (Kado, C., and Crosa, J., Eds.), 1994, pp. 491-504. Kluwer Academis Publishers, Netherlands.
40. J. H. Crosa, M. E. Tolmasky, L. Actis, and S. Falkow. Plasmids. In Methods for General and Molecular Bacteriology, (Gerhardt, P. Ed.), 1994, pp. 365-386. American Society for Microbiology.
39. L. A. Actis, M. E. Tolmasky, L. M. Crosa, and J. H. Crosa. Effect of iron-limiting conditions on the growth of clinical isolates of Acinetobacter baumanii. Presence of a chromosomally-encoded iron uptake system. Journal of Clinical Microbiology 1993 31 2812-2815.
38. M. E. Tolmasky, L. A. Actis, and J. H. Crosa. A single amino acid change in AngR, a protein encoded by virulence pJM1-like plasmids, results in hyperproduction of anguibactin. Infection and Immunity 1993 61 3228-3233.
37. A. Gammie,, M. E. Tolmasky, and J. H. Crosa. Functional characterization of the RepI replicator protein. Journal of Bacteriology 1993 175 3563-3569.
36. L. S. Waldbeser, M. E. Tolmasky, L. A. Actis, and J. H. Crosa. Mechanisms for negative regulation by iron of the fatA outer membrane protein gene expression in Vibrio anguillarum 775. Journal of Biological Chemistry 1993 268 10433-10439.
35. M. E. Tolmasky, L. A. Actis, and J. H. Crosa. Virulence plasmids. In Plasmids: A Practical Approach, (Hardy, K.G., Ed.), (The Practical Approach Series), 1993, pp. 95-118. IRL Press, Oxford University Press, Oxford, UK.
34. M. E. Tolmasky, and J. H. Crosa. Genetic organization of antibiotic resistance genes (aac(6')-Ib, aadA and oxa9) in the multiresistance transposon Tn1331. Plasmid 1993 29 31-40.
33. M. E. Tolmasky, L. A. Actis, and J. H. Crosa. Plasmids. In Encyclopedia of Microbiology, (Lederberg, J., Ed.), 1992, vol. 3, pp. 431-442. Academic Press, San Diego, California.
32. J. Echenique, H. Arienti, M. E. Tolmasky, R. Read, R. Staneloni, J. H. Crosa, and L. A. Actis. Characterization of a high affinity iron transport system in Acinetobacter baumanii. Journal of Bacteriology 1992 174 7670-7679.
31. M. E. Tolmasky, A. Gammie, and J. H. Crosa. Characterization of the recA gene of Vibrio anguillarum. Gene 1992 110 41-48.
30. A. Koster, L. A. Actis, L. Waldbesser, M. E. Tolmasky, and J. H.Crosa. Molecular charcterization of the iron transport system mediated by the pJM1 plasmid in Vibrio anguillarum 775. Journal of Biological Chemistry 1991 266 23829-2383.
29. M. E. Tolmasky, and J.H. Crosa. Regulation of plasmid-mediated iron transport and virulence in Vibrio anguillarum. Biology of Metals 1991 4 33-35.
28. S. Genti-Raimondi, M. E. Tolmasky, L. Patrito, A. Flury, and L. Actis. Molecular cloning and expression of the beta-hydroxysteroid dehydrogenase gene from Pseudomonas testosteroni. Gene 1991 105 43-49.
27. M. E. Tolmasky. Sequencing and expression of aad, bla and tnpR genes from the multiresistance transposon Tn1331. Plasmid 1990 24 218-226.
26. M. E. Tolmasky, and J.H. Crosa. Plasmid-mediated iron transport and virulence in the Fish pathogen Vibrio anguillarum. In Application of Molecular Biology in Diagnosis of Infectious diseases, (Olsvik, O. and Bukholm, G. Eds.). 1990. pp.49-54. Norwegian College of Veterinary Medicine, Norway.
25. R. Chamorro, L. Actis, J. H. Crosa, and M. E. Tolmasky. Dissemination of plasmid-mediated amikacin resistance among pathogenic Klebsiella pneumoniae. Medicina 1990 50 543-547.
24. P. , R. Chamorro, L. Actis, A. Petroni, and M. E. Tolmasky. Further characterization of Tn1331-like transposons. Anales de la Asociacion Quimica Argentina 1989 77 177-184.
23.. C. Bertinetti, M. E. Tolmasky, and R. J. Staneloni. Characterization of the extrachromosomal elements in Sclerotinia sclerotiorum. Anales de la Asociacion Quimica Argentina 1989 77 107-112.
22. P. Salinas, M. E. Tolmasky, and J. H. Crosa. Regulation of the iron uptake system in Vibrio anguillarum: evidence for a cooperative effect between two transcriptional activators. Proceedings of the National Academy of Sciences of USA 1989 86 3529-3533.
21. A. Hartstein, A. Rashad, J. Loebler, L. Actis, J. Freeman, W. Rourke, T. Stibalt, M. E. Tolmasky, G. Ellis, and J. H. Crosa. Common source multiple intensive care unit outbreak of Acinetobacter calcoaceticus subs. anitratus respiratory infection and colonization. American Journal of Medicine 1988 85 624-631.
20. K. Nobuta, M. E. Tolmasky, L. Crosa, and J. H. Crosa. Sequencing and expression of the 6'-N-acetyltransferase gene of transposon Tn1331 from Klebsiella pneumoniae. Journal of Bacteriology 1988 170 3769-3773.
19. M. E. Tolmasky, R. Chamorro, J. H. Crosa, and P. Marini. Transposon mediated amikacin resistance in Klebsiella pneumoniae.Antimicrobial Agents and Chemotherapy 1988 32 1416-1420.
18. L. A. Actis, M. E. Tolmasky, and J. H. Crosa. Genetic and molecular characterization of essential components of the Vibrio anguillarum plasmid-mediated iron transport system. Journal of Biological Chemistry 1988 263 2853-2860.
17. M. E. Tolmasky, P. Salinas, L. A. Actis, and J. H. Crosa. Increased production of siderophore activity mediated by pJM1-like plasmids in Vibrio anguillarum. Infection and Immunity 1988 56 1608-1614.
16. M. E. Tolmasky, L. A. Actis, and J. H. Crosa. Genetic analysis of the iron uptake region of the Vibrio anguillarum plasmid pJM1: molecular cloning of genetic determinants encoding a novel transactivator of siderophore biosynthesis. Journal of Bacteriology 1988 170 1913-1919.
15. M. E. Tolmasky, and J. H. Crosa. Tn1331, a novel multiresistance transposon encoding resistance to amikacin and ampicillin in Klebsiella pneumoniae. Antimicrobial Agents and Chemotherapy 1987 31 1955-1960.
14. M. E. Tolmasky, M. Roberts, M. Woloj, and J. H. Crosa. Molecular cloning of amikacin resistance determinants from a Klebsiella pneumoniae plasmid. Antimicrobial Agents and Chemotherapy 1986 30 315-320.
13. M. Woloj, M. E. Tolmasky, M. Roberts, and J. H. Crosa. Plasmid-encoded amikacin resistance in multiresistant strains of Klebsiella pneumoniae isolated from neonates with meningitis.Antimicrobial Agents and Chemotherapy 1986 29 315-319.
12. M. E. Tolmasky, L. A. Actis, A. Toranzo, J. Barja, and J. H. Crosa. Plasmid-mediated iron uptake system in Vibrio anguillarum strains isolated from turbot in Spain. Journal of General Microbiology 1985 131 1989-1997.
11. A. Zorreguieta, M. E. Tolmasky, and R. J. Staneloni. The enzymatic biosynthesis of beta 1-2 glucans. Archives of Biochemistry and Biophysics 1985 238 368-372.
10. J. H. Crosa, L. A. Actis, Y. Mitoma, J. Perez-Casal, M. E. Tolmasky, and M. A. Valvano. Plasmid-mediated iron sequestering systems in pathogenic strains of Vibrio anguillarum and Escherichia coli. In Plasmids in Bacteria, (Helinski, D. R. et al., Eds.), 1985, pp. 759-774. Plenum Publishing Corporation, New York, NY.
9. M. E. Tolmasky, and J. H. Crosa. Molecular cloning and expression of genetic determinants for the iron uptake system mediated by the Vibrio anguillarum plasmid pJM1. Journal of Bacteriology 1984 16 860-866.
8. R. J. Staneloni, M. E. Tolmasky, and L. F. Leloir. Lipid-bound saccharides containing glucose and galactose in Agrobacterium tumefaciens. Journal of General Microbiology 1984 130 869-879.
7. M. E. Tolmasky. Prenol-phospho-sugars in Rhizobium meliloti . Ph.D. Thesis, 1982, University of Buenos Aires, Argentina.
6. M. E. Tolmasky, R. J. Staneloni, and L. F. Leloir. Lipid-bound sugars in Rhizobium meliloti. Journal of Biological Chemistry 1982 257 6751-6757.
5. M. E. Tolmasky, R. J. Staneloni, and L. F. Leloir. Structural correspondence between an oligosaccharide bound to a lipid with the repeating unit of the Rhizobium meliloti exopolysaccharide. Anales de la Asociacion Quimica Argentina 1982 70 833-842.
4. M. E. Tolmasky, H. K. Takahashi, R. J. Staneloni, and L. F. Leloir. N-glycosilation of the proteins. Anales de la Asociacion Quimica Argentina 1982 70 405-411.
3. R. J. Staneloni, M. E. Tolmasky, C. Petriella, and L. F. Leloir. Transfer of oligosaccharide to protein from a lipid intermediate in plants. Plant Physiology 1981 68 1175-1179.
2. R. J. Staneloni, M. E. Tolmasky, C. Petriella, R. A. Ugalde, and L. F. Leloir. Presence in a plant of a compund similar to the dolichyl diphosphate oligosaccharide of animal tissue. Biochemical Journal 1980 191 257-260.
1. M. E. Tolmasky, R. J. Staneloni , R. A. Ugalde, and L. F. Leloir. Lipid bound sugars in Rhizobium meliloti. Archives of Biochemistry and Biophysics 1980 203 358-364.
