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Computer Lab in Molecular Systematics
Biol. 402 - Prof. Eernisse
California State University, Fullerton
Fall, 2011

Tentative Lab Schedule
(Exercises will be explained in class or provided for download on TITANium)


WEEK DATE LAB TOPIC ASSIGNMENT
1 Aug     24 Building a first tree (BOLD/MEGA/FigTree)  Exercise 1 
2 Aug     31 Phylogeny and a murder trial (Metzker et al.) and
Online genomic resources (NCBI Assignment presentations)
Exercise 2 
3 Sep     7 Mitochondrial (mt) genes across mollusks and selected outgroups Exercise 3 
4 Sep     14 Multiple sequence alignment/Tree Building Methods (PTME Chs. 4 & 5; PAUP*)
See Thompson et al. 1994 (TITANium) - Edgar 2004 (MUSCLE) - Larkin et al. 2007 (CLUSTALW2) - Goujon et al. 2010 (EMBL-EBI)
Exercise 4 alignment
5 Sep     21 Multiple sequence alignment/Tree Building Methods (cont.) Exercise 4 
6 Sep     28 Simulation of sequence evolution (Li pp. 1-11, 21-34, skim 12-20) Exercise 5 tree
7 Oct     5 Maximum Likelihood/Bayesian Inference (PTME Chs. 9 & 10) Exercise 6 
8 Oct    12 PCR and primer design (Reading TBA) Exercise 7 tube
9 Oct    19 PCR and primer design (Class Project) Exercise 7 (cont.) 
10 Oct    26 PCR and primer design (Class Project) Exercise 7 (cont.)
11 Nov    2 Applying phylogenetic methods (Start Final Project) Exercise 8 gene_map
12 Nov    9 Assembling sequence contigs Exercise 9 contigs 
13 Nov    16 Work on Final Project  
14 Nov 21-25 Fall Break No Class 
15 Nov     30 Work on Final Project No handouts 
16 Dec    7 Final Presentations TBA
Final Dec    12 FINAL PROJECTS DUE (No Exam)  5 PM - MH282

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